Engineering Halomonas species TD01 for enhanced polyhydroxyalkanoates synthesis via CRISPRi
Abstract Background Clustered regularly interspaced short palindromic repeats interference (CRISPRi) has provided an efficient approach for targeted gene inhibition.A non-model microorganism Halomonas species TD01 has been developed as a promising industrial producer of polyhydroxyalkanoates (PHA), a family of biodegradable polyesters accumulated b